Publications

Peer-reviewed papers

2021

Stukenberg D., Hensel T., Hoff J., Daniel B., Inckemann R., Tedeschi J.N., Nousch F., and Fritz G. (2021) The Marburg Collection: A Golden Gate DNA Assembly Framework for Synthetic Biology Applications in Vibrio natriegens. ACS Synth. Biol. 10, 1904–1919

Casas-Pastor D., Müller R.R., Becker A., Buttner M., Gross C., Mascher T., Goesmann A., and Fritz G. (2021), Expansion and re-classification of the extracytoplasmic function (ECF) σ factor family. Nucl. Acids Res. 49, 986-1005


2020

Oliveira R., Bush M.J., Pires S., Chandra G., Casas-Pastor D., Fritz G., and Mendes M. (2020) The novel ECF56 SigG1-RsfG system modulates morphological differentiation and metal-ion homeostasis in Streptomyces tsukubaensis. Sci. Rep. 10, 21728

Diehl A., Wood T.M., Gebhard S., Martin N.I. and Fritz G. (2020) The Cell Envelope Stress Response of Bacillus subtilis towards Laspartomycin C. Antibiotics 9, 729

Hoff J., Daniel B., Stukenberg D., Thuronyi B. W., Waldminghaus T. and Fritz G (2020) Vibrio natriegens: An ultrafast‐growing marine bacterium as emerging synthetic biology chassis. Env. Microbiol. 22, 4394–4408

Meier D., Casas-Pastor D., Fritz G. & Becker A. (2020) Gene regulation by extracytoplasmic function (ECF) σ factors in alpha-rhizobia. Adv. Bot. Res. 94, p. 289-321

Casas-Pastor D., Diehl A., Fritz G. (2020) Coevolutionary Analysis Reveals a Conserved Dual Binding Interface between Extracytoplasmic Function σ Factors and Class I Anti-σ Factors. mSystems, 5, e00310-20

Piepenbreier H., Sim A., Kobras C.M., Radeck J., Mascher T., Gebhard S. and Fritz G. (2020) From modules to networks: A systems-level analysis of the bacitracin stress response in Bacillus subtilis. mSystems, 5, e00687-19

Kobras C.M., Piepenbreier H., Emenegger J., Sim A., Fritz G. and Gebhard S (2020) BceAB-type antibiotic resistance transporters appear to act by target protection of cell wall synthesis. Antimicrob. Agents Chemother., 64, e02241-19

Iyer S.C., Casas-Pastor D., Kraus D., Mann P., Schirner K., Glatter T., Fritz G., Ringgaard S. (2020), Transcriptional regulation by σ-factor phosphorylation in bacteria. Nat. Microbiol. 5, 395–406; van der Meer J and Carraro N: Faculty Opinions Recommendation of [Iyer SC et al., Nat Microbiol 2020 5:395-406]. In Faculty Opinions, 14 Sep 2020


2019

Vecchione S. and Fritz G. (2019), CRIMoClo plasmids for modular assembly and orthogonal chromosomal integration of synthetic circuits in Escherichia coli. J. Biol. Eng. 13, 92

Hernández-Tamayo R., Oviedo Bocanegra L.O., Fritz G., and Graumann P. (2019), Symmetric activity of DNA polymerases at the Bacillus subtilis replication forks. Nucl. Acids Res., 47, 8521-8536

Piepenbreier H., Diehl A., and Fritz G. (2019), Minimal exposure of lipid II cycle intermediates triggers cell wall antibiotic resistance. Nat. Comm., 10, 2733

Mauri M., Vecchione S., and Fritz G. (2019), Deconvolution of luminescence cross-talk in high-throughput gene expression profiling. ACS Synth. Biol., 8, 1361-1370

Fritz G.*, Walker N., and Gerland U.* (2019), Heterogeneous timing of gene induction as a regulation strategy. J. Mol. Biol., 431, *corresponding authors

Wu H., Liu Q., Casas-Pastor D., Dürr F., Mascher T. & Fritz G. (2019), The role of C-terminal extensions in controlling ECF σ factor activity in the widely conserved groups ECF41 and ECF42. Mol. Microbiol. 112, 498-514

Kemter F., Schallopp N., Sperlea T., Serrania J., Sobetzko P., Fritz G., Waldminghaus T. (2019), Stringent response leads to continued cell division and a temporal re-start of DNA replication after initial shutdown in Vibrio cholerae. Mol. Microbiol., 111, 1617-1637

Keppel M.+, Piepenbreier P.+, Gaetgens C., Fritz G.*, Frunzke J.* (2019), Toxic but tasty - Temporal dynamics and network architecture of heme-responsive two-component signalling in Corynebacterium glutamicum. Mol. Microbiol. 111, 1367–1381 *corresponding authors


2018

Rösch T.C., Altenburger S., Oviedo L.M., Pediaditakis M., El Najjar N., Fritz G., and Graumann P. L. (2018), Single molecule tracking reveals spatio-temporal dynamics of bacterial DNA repair centres. Sci. Rep. 8, 16450

Rösch T.C., Oviedo L.M., Fritz G.*, and Graumann P. L.* (2018), SMTracker: a tool for quantitative analysis, exploration and visualization of single-molecule tracking data reveals highly dynamic binding of B. subtilis global repressor AbrB throughout the genome. Sci. Rep. 8, 15747

Pinto D.*, Vecchione S.*, Wu H., Mauri M., Mascher T., and Fritz G. (2018), Engineering orthogonal synthetic timer circuits based on extracytoplasmic function σ factors. Nucl. Acids Res. 46, 7450–7464

El Najjar N., El Andari J., Kaimer C., Fritz G., Rösch T.C., and Graumann P.L. (2018), Study of DNA translocases in Bacillus subtilis by single molecule tracking reveals strikingly different dynamics of SftA, SpoIIIE and FtsA. Appl. Environ. Microbiol. 84, e02610-17


2017

Becker A., Erb T. J., Fritz G., Kellmann J.-W., Sourjik V., Waldminghaus, T. (2017), Synthetische Biologie. Biol. Unserer Zeit 47, 298–305

Piepenbreier H., Fritz G.*, Gebhard S.* (2017). Transporters as information processors in bacterial signalling pathways, Mol. Microbiol. 104, 1-15

Radeck J., Fritz G., Mascher T. (2017). The cell envelope stress response of Bacillus subtilis: From static signaling devices to dynamic regulatory network. Curr. Genet. 63, 79-90


2016

Radeck J., Orchard P.S., Kirchner M., Höfler C., Gebhard S., Mascher T., and Fritz G. (2016). Anatomy of the bacitracin resistance network in Bacillus subtilis. Mol. Microbiol. 100, 607–620

Westermayer S., Fritz G., Gutiérrez J., Megerle J., Weißl M., Schnetz K., Gerland U., Rädler J. O. (2016). Single-cell characterization of metabolic switching in the sugar phosphotransferase system of Escherichia coli. Mol. Microbiol. 100, 472–485

Höfler C., Heckmann J., Fritsch A., Popp P., Gebhard S., Fritz G., Mascher T. (2016) Cannibalism stress response in Bacillus subtilis. Microbiology 162, 164-176


2015

Fritz G., Dintner S., Treichel N., Radeck J., Gerland U., Mascher T., Gebhard S. (2015). A new way of sensing: Need-based activation of antibiotic resistance by a flux-sensing mechanism. mBio 6, e00975-15

Huang X.*, Pinto D.*, Fritz G., Mascher T. (2015). Environmental sensing in Actinobacteria: A comprehensive survey on the signaling capacity of this phylum. J. Bacteriol. 197, 2517-2535


2014

Fritz G., Mascher T. (2014). A balancing act times two: Sensing and regulating cell envelope homeostasis in Bacillus subtilis. Mol. Microbiol. 94, 1201-1207

Gebhard S., Busby J.N., Fritz G., Moreland N.J., Cook G.M., Lott J.S., Baker E.N., Money V.A. (2014). Crystal structure of PhnF, a GntR-family transcriptional regulator of phosphate transport in Mycobacterium smegmatis. J. Bacteriol. 196, 3472-3481

Fritz G.*, Megerle J.A.*, Westermeyer S., Brick D., Heermann R., Jung K., Rädler J. O., Gerland U. (2014). Single cell kinetics of phenotypic switching in the arabinose utilization system of E. coli. PLoS ONE 9, e89532

Domínguez-Escobar J.*, Wolf D.*, Fritz G., Höfler C., Wedlich-Söldner R., Mascher T. (2014). Protein localization, interactions and cellular dynamics of the phage-shock protein-like Lia response in Bacillus subtilis. Mol. Microbiol. 92, 716-732


2013 and before

Radeck J.*, Kraft K.*, Bartels J., Cikovic T., Dürr F., Emenegger J., Kelterborn S., Sauer C., Fritz G., Gebhard S., Mascher T. (2013). The Bacillus BioBrick box: Generation and evaluation of essential genetic building blocks for standardized work with Bacillus subtilis. J. Biol. Eng. 7:29

Hillenbrand P., Fritz G., Gerland U. (2013). Biological signal processing with a genetic toggle switch. PLoS ONE 8, e68345.

Haneburger I.*, Fritz G.*, Jurkschat N., Tetsch L., Eichinger A., Skerra A., Gerland U., Jung K. (2012). Deactivation of the E. coli pH stress sensor CadC by cadaverine. J. Mol. Biol. 424, 15-27

Fritz K., Fritz G., Windschiegl B., Steinem C., Nickel B. (2010). Arrangement of Annexin A2 tetramer and its impact on the structure and diffusivity of supported lipid bilayers. Soft Matter 6, 4084-4094.

Fritz G., Koller C., Burdack K., Haneburger I., Tetsch L., Jung K., Gerland U. (2009). 
Induction kinetics of a conditional pH stress response system in Escherichia coli. J. Mol. Biol. 393, 272-286.

Megerle J.A.*, Fritz G.*, Gerland U., Jung K., Rädler J. O. (2008).
 Timing and dynamics of single cell gene expression in the arabinose utilization system. Biophys. J. 95:2103-2115.

Fritz G., Buchler N.E., Hwa T., Gerland U. (2007). Designing sequential transcription logic: a simple genetic circuit for conditional memory. Syst. Synth. Biol. 1, 89-98.

Mueller D.A.N., Schlichenmaier R., Fritz G., Beck C. (2006). The multi-component field topology of sunspot penumbrae - A diagnostic tool for spectropolarimetric measurements. Astron. Astrophys. 460, 925.

Schmidt W., Fritz G. (2004). On the geometry of sunspot penumbral filaments. Astron. Astrophys. 421, 735.


Conference proceedings

Müller D. A. N., Schlichenmaier R., Beck C., Fritz G. (2007) Disentangling the magnetic field structure of sunspots - Stereoscopic polarimetry with solar orbiter. Proceedings of the 2nd Solar Orbiter Workshop

Müller D. A. N., Schlichenmaier R., Fritz G., Beck C. (2006) Net circular polarization of sunspot penumbrae - A versatile tool for diagnosing magnetic field structure. Proceedings of SOHO-17